Lainey Wilson, Luis Fonsi and more stars in the St. Jude's Thanks and Giving Holiday

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Lainey Wilson, Luis Fonsi, Drew Barrymore and more stars collaborate with St. Jude's Children's Research Hospital for the 21st anniversary of the Thanks and Giving campaign to fight childhood cancer.

Sofia Vergara, John Hamm and Michael Strahan also appear in the campaign, which was released on Tuesday (November 5). The annual Thanks and Giving campaign of St. Jude encourages shoppers to support St. Jude by purchasing limited edition products from select retailers such as J. Crew, Kay Jewelers, AutoZone, JOANN, Williams Sonoma and HomeGoods or by donating online and in store.

“Music moves my soul and so do the kids at St. Jude. I am honored to have spent time with them and their families and seen first hand what supporting St. Jude really means. From learning about the impact of music therapy at St. Jude to seeing artwork from children throughout the research hospital, I continue to be inspired by the families of St. Jude,” Wilson said in a statement. “I am proud to join my country music family to bring much-needed awareness to the St. Jude Lifesaving Mission, a mission that is generously supported every day by people from all walks of life.”

“I consider St. Jude's a part of my family and take every opportunity to get involved in its life-saving mission to help increase childhood cancer survival rates around the world,” Fonsi added. “My wish this holiday season is that everyone can be reunited with their loved ones and find a way to support St. Jude.”

Williams-Sonoma customers can shop limited-edition holiday spatulas, dinnerware, candles, ornaments, gift cards and more, with proceeds going to St. Jude.

Kay Jewelers, Zales, Jared and Banter from Piercing Pagoda will donate proceeds from plush puppies and bears to St. Jude and J. Crew Factory, Factory customers can purchase co-branded products such as T-shirts, socks, ornaments with proceeds going to St. Jude.

Additionally, audiences can tune in to NBC Broadcast today daily from Monday November 25 to watch specials departments with patients of St. Jude.