Melissa McCarthy laughs at Barbra Streisand's Ozempic comment: 'I love her!'

You can't be one of America's most beloved comedians without being able to take a joke. Example: Melissa McCarthy was asked by one TMZ photographer on Tuesday (April 30) about how she felt about Barbra Streisand seemingly commenting that she was taking the weight loss drug Ozempic and was all smiles.

“I think Barbra is a treasure and I love her,” McCarthy reportedly replied when asked by paparazzi about the incident, dismissing a follow-up about whether the pop superstar/director wasn't on board with the joke.

The little dust-up started when McCarthy posted two photos on Instagram Monday of herself at the Pastels Center Theater Group gala with Hair spray director Adam Shankman. “Pastels just to honor the incredible @matthewbourne13 at the @ctgla gala last night with this guy @adamshankman!!” he wrote in the caption. “It's so much closer to my dream of dancing on stage 💃🏻💚.”

Streisand commented, “Give him my regards, did you get the Ozempic?”, a question some fans speculated the EGOT icon left thinking was a direct message to McCarthy rather than a public comment for all to see. Ozempic is a diabetes drug that has been repurposed as an anti-obesity treatment that has exploded in popularity among influencers and celebrities over the past year as many stars suddenly revealed much thinner profiles.

Streisand quickly deleted the comment and posted a mea culpa on her X profile, writing, “OMG – I went on Instagram to see the pictures we had posted of the beautiful flowers I had received for my birthday. Underneath them was a photo of my friend Melissa McCarthy who I sang with I call again album. She looked fantastic! I just wanted to give her a compliment. I forgot people read!”

McCarthy sang a duet on the classic Annie Get Your Gun tune in to “Anything You Can Do (I Can Do Better),” in 2016 I call again album, which also featured team-ups with Anne Hathaway, Alec Baldwin, Hugh Jackman, Seth MacFarlane, Jamie Foxx, and Antonio Banderas, among others. According to TMZ, since the album's release, Streisand has made a habit of posting comments on McCarthy's posts.